Head-to-head · verified 2026-08-05
MEDVi vs. TrimRx: prices, fine print, and the honest verdict
TrimRx is the cheaper tirzepatide program here — $349 vs $399 all-in at 10 mg, a $50/mo gap — but price is only the first of five things this page normalizes.
- MEDVi
- Official site
- medvi.org ↗
- Tirzepatide, all-in at 10 mg
- $399/mo
- Semaglutide, all-in
- $299/mo
- Membership fee
- None
- Prepaid / multi-month
- $249/mo effective — 12-month plan
- Commitment
- 12-month plan for the lowest rate
- Cancellation
- 12-month plan applies to lowest rate
- Pharmacy
- not named
- First-year total (standing rate)
- $4,788
- Price evidence
- Source-verified
- Last verified
- 2026-08-05
- TrimRx
- Official site
- trimrx.com ↗
- Tirzepatide, all-in at 10 mg
- $349/mo
- Semaglutide, all-in
- $299/mo
- Membership fee
- None
- Prepaid / multi-month
- $293/mo effective — 12-month plan
- Commitment
- none month-to-month
- Cancellation
- check terms before prepaying
- Pharmacy
- not named
- First-year total (standing rate)
- $4,188
- Price evidence
- Source-verified
- Last verified
- 2026-08-05
Tirzepatide pricing
On tirzepatide, TrimRx is the cheaper program at $349 a month all-in versus MEDVi's $399 — a gap of $50 a month, $600 a year, at the 10 mg maintenance basis. MEDVi: $399 a month all-in at the 10 mg maintenance basis, flat at every dose from 2.5 to 15 mg, no membership fee. Prepaid terms bring the effective rate to $249/mo (12-month plan). TrimRx: $349 a month all-in at the 10 mg maintenance basis, flat at every dose from 2.5 to 15 mg, no membership fee. Prepaid terms bring the effective rate to $293/mo (12-month plan). Prepaid terms reorder things: MEDVi at $249/mo (12-month plan) and TrimRx at $293/mo (12-month plan) — paid up front, with the regulatory-era caveat that locked-in months deserve a read of the refund terms first.
Semaglutide pricing
On semaglutide, MEDVi wins at $299 versus $299 all-in — $0/mo apart. MEDVi: Semaglutide runs $299 a month all-in at the standing rate ($179 on intro/plan terms). TrimRx: Semaglutide runs $299 a month all-in at the standing rate ($179 on intro/plan terms).
Transparency
MEDVi: Source-verified (verified 2026-08-05); dispensing pharmacy not publicly named. TrimRx: Source-verified (verified 2026-08-05); dispensing pharmacy not publicly named. In this market, a named pharmacy and a dated, source-verified price are worth real money — they are what let you check the claim instead of trusting it.
Commitment & cancellation
MEDVi: 12-month plan for the lowest rate; 12-month plan applies to lowest rate. TrimRx: none month-to-month; check terms before prepaying.
MEDVi $399/mo vs TrimRx $349/mo all-in at 10 mg — TrimRx cheaper by $50/mo ($600/yr); twelve months: $4,788 vs $4,188; best prepaid: MEDVi at $249/mo effective; semaglutide: MEDVi $299 vs TrimRx $299; verified floor $215 (NexLife); brand rails $349–$449. Basis: all-in monthly, 10 mg maintenance, capture-dated in the dataset.
The gap, compounded over time
A $50/month difference sounds decidable by coin flip until it's annualized: choosing MEDVi over TrimRx at the standing rates costs an extra one month, $50; six months, $300; a year, $600; two years of maintenance, $1,200. Prepaid, the board reshuffles: MEDVi's $249 effective edges TrimRx's $293 by $528/year — both locked up front, both worth a refund-terms read first. Every figure is the all-in maintenance basis; the arithmetic reruns from the dataset.
The 24-month ledger
Zoom to the horizon that matters for a chronic-use drug — 24 months — and MEDVi bills $9,576 and TrimRx $8,376, a spread of $1,200 for the same molecule at the same 10 mg basis. If prepaid terms held across both years, MEDVi's $249 effective would total $5,976 — $2,400 under even the cheaper standing plan, with the standing caveat that two years of locked funds in this regulatory climate is a real bet, not a rounding choice. Reference rails for the same 24 months: $5,160 at the verified floor, $10,776 on brand Zepbound at maintenance, $8,376 on Wegovy flat.
Two ladders, side by side
The 2.5-to-10 mg climb is the honest stress test: MEDVi holds $399 on every rung (four-month titration: exactly $1,596); TrimRx holds $349 on every rung (four-month titration: exactly $1,396). A flat ladder makes dose decisions purely clinical; a scaled one attaches an invoice to every escalation — including the post-plateau bump from 10 to 12.5 mg that many patients eventually face. Full framework: the titration cost guide.
Three buyers, two invoices
The month-one starter pays $399 at MEDVi versus $349 at TrimRx for the 2.5 mg rung — an early edge that holds once the ladder climbs. The settled 10 mg maintainer — the buyer our basis is built for — pays $4,188/year at TrimRx against $4,788 at the other: $600 of annual daylight for the same molecule and dose. The committed prepayer does best at MEDVi: $249/month effective, $2,988/year, funds up front, refund terms first.
The semaglutide board
MEDVi takes the semaglutide board too at $299 versus $299 all-in — a $0/month, $0/year spread. Both sit against a verified field floor of $133 and Wegovy's flat $349 brand rate; dual-molecule pricing also sets each program's internal switch cost when a plateau raises the tirzepatide question.
The five normalizations, applied to this pair
1 · All-in, not advertised. MEDVi's ranked figure is $399, with no membership to add; TrimRx's ranked figure is $349, with no membership to add. 2 · Maintenance basis. MEDVi is dose-flat, so its entry and 10 mg figures coincide; TrimRx is dose-flat, so its entry and 10 mg figures coincide. 3 · Terms separated. MEDVi: standing $399, prepaid $249 effective (12-month plan); TrimRx: standing $349, prepaid $293 effective (12-month plan) — standing rates rank, prepaid effectives are labeled beside them. 4 · Evidence tiered. MEDVi: source-verified, read 2026-08-05; TrimRx: source-verified, read 2026-08-05. 5 · Pharmacy weighed. MEDVi names no pharmacy; TrimRx names no pharmacy — in a pharmacy-variance market, disclosure is a scored asset. Run the same five on any roundup you read and most published “cheapest” lists reorder themselves.
Fine print, itemized
MEDVi: no membership — the medication figure is the billed figure; prepaid 12-month plan at $249/mo effective; 12-month plan applies to lowest rate; commitment: 12-month plan for the lowest rate. TrimRx: no membership — the medication figure is the billed figure; prepaid 12-month plan at $293/mo effective; check terms before prepaying; commitment: none month-to-month. The pattern to police on both sides is the same: memberships that outlive the medication order, renewal-relative cancellation deadlines, and prepaid terms whose refund language matters more than their discount in a year of live litigation. Cancel in writing; screenshot everything.
Transparency, audited
MEDVi carries source-verified pricing (last read 2026-08-05); its dispensing pharmacy is not publicly named, so the five pharmacy questions (name, 503A/503B status, state licensure, certificate of analysis, formulation) are your pre-purchase homework. TrimRx carries source-verified pricing (last read 2026-08-05); its dispensing pharmacy is not publicly named, so the five pharmacy questions (name, 503A/503B status, state licensure, certificate of analysis, formulation) are your pre-purchase homework. Our weighting is unapologetic: in a market of identical molecule names, a dated source-verified price and a named pharmacy are the two claims a buyer can actually check, and they carry 25 of 100 formula points between them — the methodology shows the math, and the pharmacy guide decodes every answer the five questions can return.
Switching between them
Neither program locks the door: a MEDVi-to-TrimRx move is a new intake, a new prescription at the new pharmacy, and a written cancellation at the old shop — typically a one-to-two-week overlap if you time the last fill. What does not move with you: prepaid months, membership balances, and any dose paperwork, so re-state your current rung clearly at the new intake.
Refills, shipping, and the week-to-week reality
Past the pricing page, the operational facts are what a subscriber lives with: MEDVi: shipping included; consultation included; async visit model. TrimRx: shipping included; consultation included; async visit model. Cold-chain shipments run 3–7 days across the market; the recurring failure modes are refill-timing gaps and pharmacy backlogs, so whichever program wins here, order refills a week early and confirm the pharmacy’s current turnaround at intake.
Who should pick which
Pick MEDVi if you'll prepay for the $249 effective rate. Pick TrimRx if the $50/month tirzepatide saving is the point. Neither answer is universal — which is the argument for choosing from data with dates on it rather than from whichever ad loaded first.
If neither one fits
Two programs never exhaust the market — the nearest substitutes on the verified board are Fridays at $359 (flat, no membership); Lavender Sky Health at $352 (dose-scaled, $25 membership included); Henry Meds at $349 (flat, no membership) — or skip straight to the rankings page, where every standard “cheapest / best / no-commitment” question is answered in one sourced sentence.
The brand benchmark both must beat
Neither program exists in a vacuum: FDA-approved Zepbound sits at $449/month at maintenance (LillyDirect or retail KwikPens, ~$350 on TrumpRx, ~$50 for newly eligible Medicare patients), and Wegovy at a flat $349. The cheaper of these two compounded options saves $1,200/year against the Zepbound benchmark — the number that has to justify accepting a not-FDA-reviewed product, per the full trade analysis. When a compounded quote drifts above ~$350, this benchmark starts winning the argument on its own.
The verdict
On the numbers alone, TrimRx is the cheaper tirzepatide program by $50/mo and it doesn't trade that price for opacity. Both records, with dates and sources, live in the pricing database.
Quick answers
Which is cheaper for tirzepatide, MEDVi or TrimRx?
TrimRx: $349/mo all-in at 10 mg versus $399 — a $50/mo difference ($600/yr).
Who wins on semaglutide?
TrimRx at $299/mo all-in versus $299.
Can I switch between them?
Yes — patients move between telehealth programs routinely; you'll complete the new program's intake and prescriptions restart there. If you're also switching molecule or from compounded to brand, loop in the prescriber; our switching guide covers the clinical side.
What do MEDVi and TrimRx cost over 12 months?
Who wins if I prepay?
MEDVi: $249/month effective on its 12-month plan (~$2,988/year, paid per term). Prepaying a compounded program carries refund-terms risk worth reading first.
Which is easier to cancel, MEDVi or TrimRx?
Is there a brand alternative to both?
Yes — Zepbound at $299–$449 via LillyDirect/retail (about $350 on TrumpRx; ~$50 for newly eligible Medicare patients) and Wegovy at a flat $349: FDA-approved products whose prices now sit close enough to make the comparison real.