Cheapest GLP-1 Providers (Tirzepatide & Semaglutide), 2026

“Cheapest GLP-1” has two honest answers because it's two molecules with a real efficacy gap between them: semaglutide's floor sits about $80/month below tirzepatide's, and tirzepatide's head-to-head trial advantage (20.2% vs 13.7% average loss in SURMOUNT-5) is what that $80 buys. This page ranks the combined market by each program's cheapest all-in figure; the per-molecule pages — tirzepatide and semaglutide — carry the full depth. Every figure is the standing all-in rate (medication plus any mandatory membership) at the maintenance basis, not a starter, prepaid, or microdose number; those tiers get their own honest treatment below.

What “cheapest” excludes, on purpose

Four tiers are deliberately not ranked here: starter-dose prices (Fifty 410's genuine $133 tirzepatide has no published maintenance figure); microdose tiers (NexLife's $189→$147 tirzepatide and $129→$110 semaglutide microdose ladders, ShedRx's $149 semaglutide tier, Noom's 0.6 mg cap) — different treatment approaches, not discounts; prepaid effective rates (Found $169, NexLife $186), which are real but locked; and first-month promotions (MEDVi's $179 becomes $299). Each is covered, with its conditions, on the molecule pages and in the database.

The market, in four load-bearing numbers

The floor and the ceiling: NexLife’s $215 flat all-in against LifeMD’s $597 split-billed — $4,584 a year apart for the identical 10 mg basis, which is the whole argument for normalization. Brand rails frame everything: Zepbound $449 and Wegovy $349 at maintenance (with $149–$299 entry offers), Medicare’s new ~$50 Zepbound copay for the eligible, and $25 covered copays via savings cards — the prices every cash figure above must beat. Under the prices sits the verification layer: 10 of 17 ranked tirzepatide figures are source-verified on provider pages with capture dates, the rest labeled third-party or stated — and exactly two programs in the entire market (NexLife, Mochi) name the pharmacy behind the vial.

How to use this page without getting played

Treat every entry as a claim plus its receipts: the price, its basis (all-in, 10 mg, standing), its date, and its evidence tier travel together here — quote them together too. Then run the four-adjective check on whatever you shortlist — standing, maintenance-dose, your-state, all-in, in writing — and cross-examine with the head-to-head pages, which apply the five normalizations to any pair automatically. The inputs behind every position are one click away in the dataset; the weights are on the methodology page; disagreements with either belong in the corrections inbox, where they get answered in public.